Abstract Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNAs. which are covalently closed loop structures formed by precursor mRNAs (pre-mRNAs) through back-splicing. CircRNAs are abnormally expressed in many tumors. and play critical roles in a variety of tumors as oncogenes or tumor suppressor genes by sponging miRNAs. https://www.chiggate.com/aptamil-allerpro-syneo-2-900g-online-now/