Lipoapoptosis occurring due to an excess of saturated free fatty acids such as palmitate is a key pathogenic event in the initiation of nonalcoholic fatty liver disease. Palmitate loading of cells activates the endoplasmic reticulum stress response. including induction of the proapoptotic transcription factor C/EBP homologous protein (CHOP). Furthermore. https://www.duospiritalis.com/