Knee osteoarthritis (KOA) is one of the most common degenerative diseases. and its core feature is the degeneration and damage of articular cartilage. The cartilage degeneration of KOA is due to the destruction of dynamic balance caused by the activation of chondrocytes by various factors. with oxidative stress playing an important role in the pathogenesis of KOA. https://www.duospiritalis.com/