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Fascination About indazole synthesis

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Substitution at R3 that has a halogen or alkoxy group (74f–74i) triggered a slight rise in cellular potency With all the halide analogs (74g–h) showing best the potency in the group. Further more optimization brought about the discovery of 74i–j, with 74k as probably the most Lively compound while in https://andycwmbq.mpeblog.com/55726141/the-indazole-nmr-diaries

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